by Paul Rega, MD — published on November 15th, 2009
O J Arthurs, A C Gomez, P Heinz, and P A K Set
Emerg Med J 2009; 26: 797-801. doi:10.1136/emj.2008.065177
Background: The previously mobile child who refuses to walk or weight-bearis a common presentation to the accident and emergency department,for which there are a number of causes. One uncommon cause isdiscitis, an inflammatory process of the intervertebral disc,which is easily diagnosed with spinal magnetic resonance imaging(MRI). A case series of three patients is presented of non-weight-bearingchildren in whom there was a delay in making the diagnosis oflumbosacral discitis. None presented with back pain, spinalsymptoms or abnormal neurological findings, and a full rangeof movement of both hips was found.
Methods: All patients underwent conventional radiography and ultrasound,but diagnoses were made on spinal MRI, with two patients undergoingbone scintigraphy before this.
Results: The mean delay was 15.6 days (range 13–20) from presentationat the hospital to MRI. All three patients made a good clinicalrecovery with intravenous antibiotics.
Conclusion: These cases are presented in order to heighten the awarenessof this disease entity and its imaging findings, and suggestnew guidelines for the appropriate radiological investigationsin this clinical setting.
by Paul Rega, MD — published on November 15th, 2009
L A Jones and S Goodacre
Emerg Med J 2009; 26: 783-785. doi:10.1136/emj.2008.065938
Background: A recent meta-analysis showed that intravenous and nebulisedmagnesium sulphate have similar levels of evidence to supporttheir use in the treatment of acute asthma in adults. This consistedof weak evidence of effect on respiratory function and hospitaladmissions, with wide confidence intervals ranging from no effectto significant positive effects. Current BTS/SIGN guidelinessuggest an equivocal role for intravenous magnesium sulphateand no role for nebulised magnesium sulphate. A study was performedto assess what emergency physicians currently do in their managementof acute asthma.
Method: A postal survey was undertaken of all adult emergency departmentswithin the UK. A structured questionnaire was sent to all clinicalleads in emergency medicine about their current usage of bothintravenous and nebulised magnesium sulphate in the treatmentof acute asthma.
Results: 180 of the 251 emergency departments in the UK responded (72%).Magnesium sulphate was used in 93%, mostly because it was expectedto relieve breathlessness (70%) or reduce HDU/ITU admissions(51%). It was predominantly given to those patients with acutesevere asthma (84%) and life-threatening exacerbations (87%),with most stating they would give the drug if there was no responseto repeated nebulisers (68%). In comparison, nebulised magnesiumsulphate was only used in two emergency departments (1%). Themain reason for not administering the drug via a nebuliser wasinsufficient evidence (51%).
Conclusions: Intravenous magnesium sulphate is widely used for acute asthma,usually for patients with severe or life-threatening asthmawho have not responded to initial treatment. Nebulised magnesiumsulphate, by contrast, is hardly used at all. The use of intravenousmagnesium sulphate is more extensive than current guidelinesor available evidence would appear to support.
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