Archive for February, 2011

Babygrams

http://www.nytimes.com/2011/02/28/health/28radiation.html?_r=1&nl=todaysheadlines&emc=tha23

NY Times

February 27, 2011′
X-Rays and Unshielded Infants
By WALT BOGDANICH and KRISTINA REBELO

“…….anguish and shame over the discovery that the tiniest, most vulnerable of all patients — premature babies — had been over-radiated in the department…….at State University of New York Downstate Medical Center in Brooklyn.

A day earlier, ……..a newborn had been irradiated from head to toe — with no gonadal shielding — even though only a simple chest X-ray had been ordered…….

……And the problems did not end there……..the hospital’s new pediatric radiologist found that full-body X-rays of premature babies had occurred often, that radiation levels on powerful CT scanners had been set too high for infants, and that babies had been poorly positioned, making it hard for doctors to interpret the images……….”

Nanoparticles

http://www.news-medical.net/news/20110223/Nanoparticle-therapy-may-improve-survival-after-life-threatening-blood-loss.aspx

Nanoparticle therapy may improve survival after life-threatening blood loss

23. February 2011 02:45

“In an advance that could improve battlefield and trauma care, scientists at Albert Einstein College of Medicine of Yeshiva University have used tiny particles called nanoparticles to improve survival after life-threatening blood loss.

Nanoparticles containing nitric oxide (NO) were infused into the bloodstream of hamsters, where they helped maintain blood circulation and protect vital organs. The research was reported in the February 21 online edition of the journal Resuscitation…..”

Jail time for ER assaults

http://www.wset.com/Global/story.asp?S=14058019

Va bill requiring jail time for ER assaults passes

RICHMOND, Va. (AP) – “Those who assault emergency room workers would spend at least two days in jail under a bill that is headed to Gov. Bob McDonnell.  The Senate gave final passage to Del. Christopher Stolle’s bill on a 33-7 vote Friday. It passed the House earlier on a 92-7 vote……

Stolle said emergency room employees are 400% more likely to be assaulted than the average U.S. worker….”

Danger: Cribs, Playpens and Bassinets

http://www.healthcanal.com/public-health-safety/14621-New-National-Study-Finds-9500-Emergency-Department-Visits-Related-Cribs-Playpens-and-Bassinets-Each-Year.html

HealthCanal.com

New National Study Finds 9,500 Emergency Department Visits Related to Cribs, Playpens and Bassinets Each Year in U.S.

“…….A new study conducted by researchers at the Center for Injury Research and Policy of The Research Institute at Nationwide Children’s Hospital examined injuries associated with cribs, playpens and bassinets among children younger than 2 years of age from 1990 through 2008.  During the 19-year study period, an average of 9,500 injuries and more than 100 deaths related to these products were seen in U.S. emergency departments each year……the majority of the injuries involved cribs (83 percent) and the most common injury diagnosis was soft-tissue injury (34 percent), followed by concussion or head injury (21 percent). The head or neck was the most frequently injured body region (40 percent), followed by the face (28 percent). Two-thirds of the injuries were the result of a fall, and the percentage of injuries attributed to falls increased with age……..”

Facial recognition technology in the ER

http://www.securitydirectornews.com/?p=article&id=sd201102qFTCS

Hospital uses facial recognition, other technology to identify high-risk people
By Leischen Stelter02.22.2011  

“….The hospital is using a variety of technology to alert staff of potentially dangerous individuals. Facial recognition technology has been deployed in its emergency department to identify people within the hospital’s database who are considered high risk…..”

OraQuick HCV Rapid Antibody Test

http://www.medpagetoday.com/PrimaryCare/PreventiveCare/25027

http://www.medpagetoday.com/InfectiousDisease/Hepatitis/20906

WASHINGTON — “The FDA has approved the use of blood obtained through a finger stick for a hepatitis C virus (HCV) test.

The OraQuick HCV Rapid Antibody Test was initially approved in June 2010 for use with a venous whole blood sample….”

21,000 people got whooping cough

AP
By MIKE STOBBE, AP Medical Writer Mike Stobbe,
AP Medical Writer Wed Feb 23, 3:00 pm ET

ATLANTA – “More than 21,000 people got whooping cough last year, many of them children and teens. That’s the highest number since 2005 and among the worst years in more than half a century, U.S. health officials said Wednesday.

They are puzzled by the sharp rise in cases. The vaccine against whooping cough is highly effective in children, and vaccination rates for kids are good….”

Extenze Tablets: Recall

http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm244369.htm

Extenze Tablets: Recall

[Posted 02/23/2011]

AUDIENCE: Consumer

ISSUE: FDA notified Biotab Nutraceuticals, Inc. that two lots of counterfeit product purporting to be Extenze contain undeclared drug ingredients. Specifically, lot 0709241 contains tadalafil and sildenafil, and lot 0509075 contains tadalafil and sibutramine.

Tadalafil and sildenafil are drugs used to treat erectile dysfunction (ED). These drugs may interact with nitrates found in some prescription drugs (such as nitroglycerin) and may lower blood pressure to dangerous levels. Consumers with diabetes, high blood pressure, high cholesterol, or heart disease often take nitrates. ED is a common problem in men with these conditions, and consumers may seek Extenze to enhance sexual performance.

Sibutramine is a controlled substance that was withdrawn from the market in October 2010 for safety reasons. Sibutramine is known to substantially increase blood pressure and/or pulse rate in some patients and may present a significant risk for patients with a history of coronary artery disease, congestive heart failure, arrhythmias or stroke.

BACKGROUND: The counterfeit products are sold at retail nationwide in the form of carded four-packs (lot 0709241) and in the form of a box of thirty tablets divided into two fifteen tablet blister packs (lot 0509075). It is possible that there may be other counterfeit products on the market that have yet to be identified.

RECOMMENDATION: Consumers in possession of product from the lots in question only should return any unused product.

Identifying and containing norovirus outbreaks

http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm244331.htm

FDA NEWS RELEASE

For Immediate Release: Feb. 23, 2011
Media Inquiries: Erica Jefferson, 301-796-4988, erica.jefferson@fda.hhs.gov
Consumer Inquiries: 888-INFO-FDA

FDA permits marketing of first test for most common cause of gastroenteritis outbreaks
Test can aid in identifying and containing norovirus outbreaks

The U.S. Food and Drug Administration allowed marketing of the first test for the preliminary identification of norovirus.

The Ridascreen Norovirus 3rd Generation EIA assay is for use when a number of people have simultaneously contracted gastroenteritis and there is a clear avenue for virus transmission, such as a shared location or food.

Norovirus is a leading cause of food-borne disease outbreaks in the United States.

Acute gastroenteritis is an inflammation of the stomach and intestine that can cause diarrhea, vomiting and stomach pain. Norovirus contamination usually occurs in settings where there is close group contact, such as cruise ships, hospitals, long-term care facilities, and schools or child-care centers. It is a highly contagious virus that spreads rapidly through direct person-to-person contact, contaminated food or water, and by touching contaminated surfaces.  

 “This test provides an avenue for early identification of norovirus,” said Jeffrey Shuren, M.D., J.D., director of the FDA’s Center for Devices and Radiological Health. “Early intervention can halt the spread of an outbreak.”

The test is not sensitive enough for use when only a single person has symptoms and should not be used for diagnosing individual patients.  

The manufacturer demonstrated the performance of the Ridascreen test by comparing results of it to the results of a norovirus reference standard for 609 fecal samples. When the fecal samples were tested with Ridascreen, overall results on average were less sensitive than those of standard reference tests, detecting norovirus across samples about 2/3 of the time it was present.

The FDA reviewed data for Ridascreen via the de novo pathway, an alternative path to market for devices that are lower risk and may not require premarket approval (PMA), but are of a new type, and therefore may not be able to be cleared in a ‘510(k)’ premarket notification.

In March, the U.S. Centers for Disease Control and Prevention will be updating management and disease prevention guidelines for norovirus outbreaks. These guidelines will likely reflect substantial advances made in norovirus epidemiology, immunology, diagnostic methods and infection control. 

Ridascreen is made by R-Biopharm AG, located in Darmstadt, Germany.

Minor head injury in anticoagulated patients

Emergency management of minor head injury in anticoagulated patients

A Leiblich, S Mason

Emerg Med J 2011;28:115-118 Published Online First: 25 November 2010 doi:10.1136/emj.2009.079442

http://emj.bmj.com/content/28/2/115.abstract

Flu in NWO

Ohio Flu Update:

ODH reports that there were 18 hospitalized flu cases in the NW Ohio region for MMWR Week 6 (Feb 6-12, 2011).  The percentage of ER visits for patients with consstitutional symptoms has remained above baseline in the state for  the bast five weeks.  Thermometer sales are below the statewide baseline.  Sentinel site providers reported 2.42% of patients had ILI signs and symptoms in the past week.  Last week, MMWR week 5, 3.9% of visits were for ILI.  There have been no pediatric flu related deaths reported for the 2010-11 year in Ohio.232 hospitalized flu cases were reported to ODH in the past week.

Teen Births

http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6006a6.htm?s_cid=mm6006a6_e&source=govdelivery

QuickStats: Birth Rates* for Teens Aged 15–19 Years, by State — United States, 2009

MMWR WeeklyFebruary 18, 2011 / 60(06);183

 

Influenza-like illness (ILI) visits and deaths

Percentage of visits for influenza-like illness (ILI) reported, by surveillance week and year — U.S. Outpatient Influenza-Like Illness Surveillance Network (ILINet), United States, September 30, 2007–February 5, 2011

Pneumonia and Influenza-Related Mortality

For the week ending February 5, 2011, pneumonia and influenza (P&I) was reported as an underlying or contributing cause of death for 8.0% of all deaths reported to the 122 Cities Mortality Reporting System. This percentage is at the epidemic threshold of 7.97% for that week.¶¶ Since October 3, 2010, the weekly percentage of deaths attributed to P&I ranged from 6.0% to 8.4%, and first exceeded the epidemic threshold during the week ending January 29, 2011 (Figure 4). Peak weekly percentages of deaths attributed to P&I previously were as follows: 8.2 for the week ending January 23, 2010, during the 2009–10 season; 7.9 for the week ending April 11, 2009, during the 2008–09 season; 9.1% for the week ending March 15, 2008, during the 2007–08 season; and 7.7% for the week ending February 24, 2007, during the 2006–07 season.

Influenza-Related Pediatric Mortality

As of February 5, 2011, a total of 30 influenza-related pediatric deaths from 18 states (Arizona, Colorado, Florida, Georgia, Illinois, Indiana, Louisiana, Michigan, New Jersey, New York, North Carolina, North Dakota, Oklahoma, Pennsylvania, Texas, Utah, Virginia, and West Virginia) and New York City have been reported to CDC for the 2010–11 season. Nine deaths were associated with influenza A (H3N2) virus infection, 12 deaths were associated with influenza B virus infection, three deaths were associated with influenza A (H1N1), and six were associated with an influenza A virus for which the subtype was not determined. Twenty of these deaths occurred during January 16–February 5, 2011. During the 2009 pandemic, 329 pediatric deaths were reported during April 15, 2009–January 23, 2010. Before the pandemic, 65 influenza-related pediatric deaths were reported for the 2008–09 season (through the week ending April 11, 2009), 88 pediatric deaths were reported for the 2007–08 season, and 77 pediatric deaths were reported for the 2006–07 season.

http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6006a4.htm?s_cid=mm6006a4_e&source=govdelivery

Estimating Actual Body Weight in the ER

Bedside Method to Estimate Actual Body Weight in the Emergency Department
Published online: 22 February 2011
Robert G. Buckley, Christine R. Stehman, Frank L. Dos Santos, Robert H.
Riffenburgh, Aaron Swenson, Nathan Mjos, Matt Brewer, Sheila Mulligan
DOI: 10.1016/j.jemermed.2010.10.022
Journal of Emergency Medicine, The,

http://www.jem-journal.com/article/S0736-4679%2810%2901010-3/abstract

What happens when there is a loss of water service……Disease!

http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6006a1.htm?s_cid=mm6006a1_e&source=govdelivery

Community Health Impact of Extended Loss of Water Service — Alabama, January 2010

MMWR WeeklyFebruary 18, 2011 / 60(06);161-166

 

Access to clean water is fundamental to good health (1). During January 2010, approximately 18,000 residents of two predominantly rural counties in Alabama lost access to municipal water for up to 12 days after below-freezing temperatures led to breaks in water mains and residential water pipes and caused widespread systemic mechanical failures. To assess potential health impacts, use of alternative water sources, and effectiveness of the emergency response, the Alabama Department of Public Health (ADPH) invited CDC to assist in an investigation that included a survey of 470 households representing 1,283 residents and a qualitative investigation (i.e., focus group discussions and interviews with key informants). This report summarizes the results of that investigation, which found a significantly higher prevalence of acute gastrointestinal illness (AGI) among residents of households that lost both water service and water pressure (adjusted odds ratio [AOR] = 2.6), that lost water service for ≥7 days (AOR = 2.4), and that lost water pressure for ≥7 days (AOR = 3.5). Significant dose-response relationships were observed between increased duration of lost water service or pressure and AGI. The survey and qualitative investigation revealed that households, communities, water utilities, and institutions were not adequately prepared for water emergencies in areas of communication and notification, planning for alternative water sources, and interagency coordination. Health effects from loss of water supply or water pressure might be mitigated by public health involvement in fostering household, community, and interagency preparedness, and developing communication strategies that will reach the majority of citizens in a timely manner.

Community A and community B are located in two contiguous, predominantly rural counties in southwestern Alabama, served primarily by three interconnected public water utilities. Because freezing conditions are rare in this area, few building code regulations require burial or insulation of residential water pipes. During January 4–11, 2010, overnight low temperatures ranged from 12°F to 22°F (-11°C to -6°C), causing many utility water mains and residential water pipes to break. The resulting systemic water loss and related mechanical failures forced water utilities to cut off service to most households in the two communities (Figure). Local ADPH offices did not learn about the water shortages until January 10 in community A, when a resident complained about restaurants operating without water, and January 11 in community B, when an ADPH nurse found a school operating without water. Subsequently, ADPH issued boil water advisories for both communities. Three agencies were involved in supplying emergency water to the affected communities: the Alabama Emergency Management Agency provided five truckloads of bottled water to community A and one truckload to community B; the National Guard delivered nonpotable water to community A; and ADPH deployed water filtration/UV disinfection units to both communities……

Results

610 (68%) that were eligible for inclusion.

“…..Of those, a respondent in 470 (77%) households completed the survey, providing data on 1,283 persons. Median age of the 1,283 was 36 years (range: 0–94 years), and 54% were female; 55% were black, and 44% were white. Demographic characteristics of respondents were similar to census data for both counties.

Among households with no loss of water service or pressure, AGI was reported for 13 (4.3%) residents during January 4–31. AGI was associated with combined loss of water service and pressure (67 residents [12.4%], AOR = 2.6), loss of service ≥7 days (46 [13.2%], AOR = 2.4), and loss of pressure ≥7 days (23 [15.6%], AOR = 3.5) and 3–6 days (30 [12.7%], AOR = 2.8). Dose-response relationships were evident for the duration of both loss of service and loss of pressure (p for trend = 0.03 and 0.002, respectively) (Table).

The prevalence of ARI among unaffected households was 13.9%. Although individual AORs were not statistically significant, reporting of ARI increased with increasing duration of loss of pressure (1–2 days, 12.8%; 3–6 days, 20.5%; ≥7 days, 22.8%; p-value for trend = 0.04). Loss of water service was not associated with ARI. A total of 25 persons (1.6%) reported skin complaints, and 15 (1.0%) reported eye complaints; these outcomes were not significantly associated with loss of service or pressure.

Of the 470 surveyed households, 108 (23%) reported water pipe breaks as a result of the January freeze. A total of 210 (45%) of the 470 households had any water stored for emergencies, and <10% had stored >5 gallons. Among households in community A and community B, which were under a boil water advisory, residents in 90% of the households had heard about the advisory. However, <50% heard about it at the beginning of the water emergency, and 30% reported drinking unboiled tap water. In community B, residents in 40% of the households said they heard about the boil water advisory from family, friends, or neighbors, and not from official sources. In both community A and community B, residents preferred to hear emergency information via telephone (73.4% and 59.1%, respectively), television (37.4% and 42.4%), or radio (42.4% and 24.2%), compared with informal sources such as friends and neighbors (15.1% and 9.1%) (preferences were not mutually exclusive)……

Editorial Note

In this investigation, the prevalence of AGI in households unaffected by the January 2010 water emergency (4.3%) was similar to the national 1-month background prevalence (5.1%) of acute diarrheal illness identified in FoodNet population surveys (2), whereas the prevalence of AGI in the most affected households was significantly higher (12.4%–15.6%). Of 780 drinking water–associated outbreaks reported in the United States during 1971–2006, 10% were associated with water distribution system deficiencies (3). Although a limited number of epidemiologic studies have investigated the association between low water pressure and illness, some have identified increased AGI in populations experiencing low water pressure (4–6). Even without loss of water service, brief periods of low pressure lasting only seconds (pressure transients) can draw contaminants into the distribution system through numerous cracks and leaks in water pipes (7) or back-siphonage from household plumbing systems that lack adequate backflow prevention devices. The findings from this investigation suggest that additional studies are needed to assess the prevalence of waterborne disease attributable to water distribution systems……..

References

  1. World Health Organization. Guidelines for drinking-water quality. 3rd ed. Geneva, Switzerland: World Health Organization; 2008. Available at http://www.who.int/water_sanitation_health/dwq/fulltext.pdf . Accessed February 14, 2011.
  2. Jones TF, McMillian MB, Scallan E, et al. A population-based estimate of the substantial burden of diarrhoeal disease in the United States; FoodNet, 1996–2003. Epidemiol Infect 2007;135:293–301.
  3. Craun GF, Brunkard JM, Yoder JS, et al. Causes of outbreaks associated with drinking water in the United States from 1971 to 2006. Clin Microbiol Rev 2010;23:507–28.
  4. Hunter PR, Chalmers RM, Hughes S, Syed Q. Self-reported diarrhea in a control group: a strong association with reporting of low-pressure events in tap water. Clin Infect Dis 2005;40:e32–4.
  5. Nygard K, Wahl E, Krogh T, et al. Breaks and maintenance work in the water distribution systems and gastrointestinal illness: a cohort study. Int J Epidemiol 2007;36:873–80.
  6. Payment P, Siemiatycki J, Richardson L, Renaud G, Franco E, Prevost M. A prospective epidemiological study of gastrointestinal health effects due to the consumption of drinking water. Int J Environ Health Res 1997;7:5–31.
  7. LeChevallier MW, Gullick RW, Karim MR, Friedman M, Funk JE. The potential for health risks from intrusion of contaminants into the distribution system from pressure transients. J Water Health 2003;1:3–14.
  8. Hennessy TW, Ritter T, Holman RC, et al. The relationship between in-home water service and the risk of respiratory tract, skin, and gastrointestinal tract infections among rural Alaska natives. Am J Public Health 2008;98:2072–8.
  9. Kirmeyer G, Richards W, Smith C. An assessment of water distribution systems and associated research needs. Denver, CO: American Water Works Association Research Foundation; 1994.
  10. American Water Works Association. Dawn of the replacement era: reinvesting in drinking water infrastructure. Denver, CO: American Water Works Association; 2001. Available at http://www.win-water.org/reports/infrastructure.pdf . Accessed February 14, 2011.